Status:

RECRUITING

Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants

Lead Sponsor:

Crouse Hospital

Conditions:

Poor Growth in Extremely Preterm Infants

Necrotizing Enterocolitis

Eligibility:

All Genders

Up to 6 years

Phase:

NA

Brief Summary

The aim of the project is to study the effects of fortification (using a Human Milk Donor Fortifier) of an exclusive preterm human milk diet on outcome of extremely preterm neonates, born at less or e...

Detailed Description

II. BACKGROUND Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease affecting \>10% of extremely preterm infants with a mortality of up to 50%. The pathophysiology is poorly understoo...

Eligibility Criteria

Inclusion

  • All extremely preterm infants with gestational age less or equal to 27 weeks who are admitted to the NICU prior to day of life seven and the first enteral feeding

Exclusion

  • Infants with severe congenital anomalies such as chromosomal trisomy, congenital heart disease, and abdominal wall defect

Key Trial Info

Start Date :

February 15 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2027

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04284280

Start Date

February 15 2020

End Date

February 1 2027

Last Update

February 13 2023

Active Locations (1)

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1

Crouse Hospital

Syracuse, New York, United States, 13210