Status:
COMPLETED
Embryo Developmental Potential in a Novel 2-step IVM System
Lead Sponsor:
Universitair Ziekenhuis Brussel
Conditions:
In Vitro Maturation of Oocytes
Eligibility:
FEMALE
18-36 years
Phase:
NA
Brief Summary
In vitro maturation is a valid option for PCO(S) patients in the daily ART clinic, however maturation and embryologic development are not yet matching the efficiency levels obtained by standard COS tr...
Detailed Description
The current IVM system in use in the clinic has a single step approach and seems to be less efficient compared to research and literature findings using a biphasic CAPA-IVM system in terms of maturati...
Eligibility Criteria
Inclusion
- PCO(S) patients
- Anti-Mullerian Hormone ≥ 3.6 ng/mL
- Basal Antral Follicle Count ≥ 20
- All ranks of trial
Exclusion
- Surgically obtained semen sample
- Grade 3 or 4 endometriosis, minor or major uterine abnormalities
- Preimplantation Genetic Testing
- Priming with Letrozole
Key Trial Info
Start Date :
July 16 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT04285892
Start Date
July 16 2020
End Date
December 31 2023
Last Update
November 25 2024
Active Locations (1)
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1
UZ Brussel
Brussels, Belgium, 1090