Status:

UNKNOWN

Influence of Pb&Cd Seminal Plasma Level & ICSI

Lead Sponsor:

Assiut University

Conditions:

Infertility, Male

Eligibility:

All Genders

18-75 years

Brief Summary

To evaluate the influence of lead (pb) and cadmium (cd) seminal plasma level on embryo development and pregnancy rate during intracytoplasmic sperm injection (ICSI).

Detailed Description

The inability to have children, both by natural procreation and medically assisted reproduction, is not only a challenge for medical science but also an economic and social problem. Infertility is a c...

Eligibility Criteria

Inclusion

  • Isolated male infertility (oligozoospermia, astenozoospermia, teratozoospermia)
  • First ICSI cycle
  • Female partner ≤ 35 y-old

Exclusion

  • • Wife age \> 35 years
  • Frozen semen samples
  • Male partner with severe oligoasthenoteratozoospermia \<5 × 106 / mL and 5% progressive motility, included globozoospermia and pinhead samples, and surgically retrieved sperms
  • Poor responder women
  • Women with abnormal endometrium at hCG trigger day.
  • Women with BMI \> 31
  • Women with PCOS
  • Previous failed ICSI
  • OHSS)overian hyperstimulation syndrome)
  • Patients with systemic diseases affecting fertility
  • Patients on radiotherapy or receiving medications with gonadotoxic effect eg., chemotherapy

Key Trial Info

Start Date :

May 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04286633

Start Date

May 1 2022

End Date

December 1 2022

Last Update

July 23 2021

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