Status:
ACTIVE_NOT_RECRUITING
Memory Retrieval and Encoding Investigated by Neural Stimulation
Lead Sponsor:
University of Pennsylvania
Collaborating Sponsors:
National Institute of Neurological Disorders and Stroke (NINDS)
Columbia University
Conditions:
Epilepsy Intractable
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of...
Eligibility Criteria
Inclusion
- Expected to undergo intracranial implantation and postoperative electroencephalographic monitoring as part of a standard clinical procedure for the treatment of pharmacologically resistant epilepsy
- Age 18 or older
Exclusion
- Any physical or cognitive disability or illness that would limit their ability to perform cognitive tasks
- Any medical condition that would, in the investigator's opinion, limit the subject's participation in the study.
- Unable or unwilling to provide informed consent
- MRI contraindications
- Standard clinical care includes a pregnancy test for female patients prior to the surgical implantation of the electrodes. Pregnant women are not surgically implanted.
Key Trial Info
Start Date :
October 12 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
800 Patients enrolled
Trial Details
Trial ID
NCT04286776
Start Date
October 12 2014
End Date
December 31 2024
Last Update
November 5 2024
Active Locations (11)
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1
University of Colorado, Denver
Aurora, Colorado, United States, 80045
2
Emory University Hospital
Atlanta, Georgia, United States, 30322
3
National Institute of Neurological Disorders and Stroke
Bethesda, Maryland, United States, 20892
4
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215