Status:

COMPLETED

Teen Adherence in KidnEy Transplant Improving Tracking To Optimize Outcomes - Stage 3

Lead Sponsor:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Collaborating Sponsors:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

Medication Adherence

Kidney Transplantation

Eligibility:

All Genders

12-24 years

Phase:

NA

Brief Summary

Medication non-adherence is a major problem in kidney transplant recipients; young people 12-24 years of age are at particularly high risk for non-adherence and graft failure compared to young childre...

Detailed Description

This entry describes Stage 3 of the study. In Stage 3, the adapted intervention and new e-pillbox and adherence-tracking website will be piloted in preparation for a definitive cluster-randomized tria...

Eligibility Criteria

Inclusion

  • Patient Inclusion Criteria
  • kidney-only transplant recipients, who are ≥3 months post-transplant
  • Aged 12 to 24 years
  • Patients followed at one of the study sites
  • Patient Exclusion Criteria
  • Patients with significant neurocognitive disabilities limiting their ability to understand and participate in their own care (as judged by the parents and the healthcare team)
  • Patients unable to communicate in English or French (Montreal sites only)
  • Multi-organ transplant recipients
  • Patient has a sibling participating in Stage 3
  • Patients with no internet access
  • Parents Inclusion Criteria • Parent of prevalent kidney-only transplant recipients 12-17 y (followed in a participating transplant center) will be eligible
  • Parents Exclusion Criteria
  • • Parents of patients 18-24 years old will be excluded as the older aged group is expected to be primarily responsible for their own care, independent of their parents. One parent per family will be eligible to avoid redundant representation.
  • Health Care Professionals Inclusion Criteria
  • Representatives from the variety of disciplines typically involved in promoting medication adherence as deemed appropriate from each center.
  • HCP from adherence intervention sites

Exclusion

    Key Trial Info

    Start Date :

    February 4 2022

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    June 30 2023

    Estimated Enrollment :

    96 Patients enrolled

    Trial Details

    Trial ID

    NCT04288271

    Start Date

    February 4 2022

    End Date

    June 30 2023

    Last Update

    March 15 2024

    Active Locations (8)

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    Page 1 of 2 (8 locations)

    1

    St-Louis Children's Hospital

    St Louis, Missouri, United States, 63110-1002

    2

    Temple University

    Philadelphia, Pennsylvania, United States, 19140-5102

    3

    University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, United States, 15213-2536

    4

    Seattle Children's Hospital

    Seattle, Washington, United States, 98105-3901