Status:

UNKNOWN

Evaluation of the Efficacy of Captopril Versus Propranolol and Timolol as a Treatment of Infantile Capillary Hemangioma

Lead Sponsor:

Ain Shams University

Conditions:

Infantile Hemangioma

Eligibility:

All Genders

2-12 years

Phase:

PHASE4

Brief Summary

Is to compare and evaluate the efficacy of oral captopril with oral propranolol, intralesional propranolol injection, and topical Timolol in the treatment of infantile hemangioma and their effect on v...

Detailed Description

Infantile hemangiomas are the most common benign tumor of infancy, affecting up to 10% of the pediatric population with a higher incidence in female (3:1), preterm infants, and Caucasian population. T...

Eligibility Criteria

Inclusion

  • Pediatric patients younger than 12 years and older than 2 months of age with infantile hemangioma

Exclusion

  • Patient with ulcerated or infected hemangioma.
  • Patient younger than 2 months and older than 12 years of age.
  • Patients with multiple hemangiomas.
  • Any Patient with cardiovascular problems, bronchial asthma, diabetes mellitus, bilateral renal stenosis, Electrolyte disturbance, or renal impairment was excluded.
  • Patients with abnormal electrocardiogram, or echocardiogram should be excluded.
  • Patients who have had previous treatment for hemangioma.

Key Trial Info

Start Date :

October 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2021

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04288700

Start Date

October 1 2019

End Date

October 1 2021

Last Update

February 28 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Vascular malformation clinic of Pediatric Surgery department of Ain Shams University.

Cairo, Egypt