Status:
WITHDRAWN
Nitric Oxide Gas Inhalation for Severe Acute Respiratory Syndrome in COVID-19.
Lead Sponsor:
Xijing Hospital
Conditions:
Coronavirus Covid-19 Infection Variant Omicron
SARS (Severe Acute Respiratory Syndrome)
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The investigators will enroll 104 patients with severe COVID-19 infection that mechanical ventilation is needed for respiratory support. Patients will be randomized to receive either inhaled nitric ox...
Detailed Description
The outbreak of COVID-19 and its global pandemic have posed a threat to public health. The deadly virus, SARS-CoV-2, has been evolving to new, more infectious variant and other lineages with additiona...
Eligibility Criteria
Inclusion
- Age ≥18 years
- Diagnosed Covid-19 infection
- Severe cases of Covid-19 infection needs mechanical ventilation
Exclusion
- Physician makes a decision that trial involvement is not in the patient's best interest or any condition that does not allow the protocol to be followed safely
- Pregnant or positive pregnancy test in a pre-dose examination
- mechanical ventilation initiated for more than 48 hrs
- Rescue Use ECMO
- With severe organ dysfunction or failure (Child Pugh≥12, eGFRC30 ml/min/1.73m2, on RRT or dialysis)
Key Trial Info
Start Date :
January 16 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2024
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04290871
Start Date
January 16 2023
End Date
April 1 2024
Last Update
February 8 2023
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