Status:
NOT_YET_RECRUITING
Prospective Study of Induction Medications Used in the Trauma RSI
Lead Sponsor:
University of Southern California
Collaborating Sponsors:
University of California, Irvine
University of Texas
Conditions:
Trauma
Rapid Sequence Intubation
Eligibility:
All Genders
18+ years
Brief Summary
To compare the outcomes of the use of propofol, etomidate, and ketamine as induction agents for adult trauma patients undergoing intubation within 24 hours of admission. The primary goal is to determi...
Detailed Description
Rationale: Although rapid sequence intubation (RSI) is commonly used in the emergency department (ED) or operating room (OR) for trauma patients, there is not one induction medication which has been ...
Eligibility Criteria
Inclusion
- Trauma patients \>=18 yo requiring intubation within 24 hours of admission in either the ED or OR
- Patients received propofol, etomidate, or ketamine for induction agent
Exclusion
- Patients who were intubated without induction agent medications
- Patients intubated outside of the hospital or in the field
- Patients who were intubated with an induction agent other than etomidate, ketamine, or propofol
Key Trial Info
Start Date :
January 1 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 30 2028
Estimated Enrollment :
7000 Patients enrolled
Trial Details
Trial ID
NCT04291521
Start Date
January 1 2026
End Date
July 30 2028
Last Update
March 5 2024
Active Locations (1)
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1
Keck School of Medicine of the University of Southern California
Los Angeles, California, United States, 90033