Status:
UNKNOWN
Predictors of Rejection in Pediatric Kidney Transplantation
Lead Sponsor:
Assiut University
Conditions:
Rejection Acute Renal
Eligibility:
All Genders
4-18 years
Brief Summary
Renal transplantation is the best option among the end-stage renal disease (ESRD) treatment alternatives, It is also relatively less expensive than dialysis. Allograft rejection is a major issue in ki...
Detailed Description
The most common medication regimen in the United States includes the combination of corticosteroid (eg, prednisone), a calcineurin inhibitor (or CNI, most commonly tacrolimus), and an antimetabolite s...
Eligibility Criteria
Inclusion
- Paediatric living donor kidney transplant recipients (aged 1-18 years)
- patients received standard triple drug immunosuppression consisting tacrolimus an antiproliferative drug \[mycophenolate mofetil (MMF) and steroids
- recipients with biopsy proven acute rejection in the studied group.
Exclusion
- patients on cyclosporine
- patients with active infection and dehydration
- Patients who received multiorgan transplantation Non cooperative patient will be excluded
Key Trial Info
Start Date :
May 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2021
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT04292418
Start Date
May 1 2020
End Date
October 1 2021
Last Update
March 3 2020
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