Status:
UNKNOWN
Thin Endometrium Undergoing Frozen-thawed Embryo Transfer
Lead Sponsor:
Nanjing University
Conditions:
Thin Endometrium
Eligibility:
FEMALE
20-37 years
Phase:
NA
Brief Summary
The endometrium is essential for embryo implantation. The clinical pregnancy rate and live birth rate of patients with thin endometrium are significantly lower than those of normal endometrium. Previo...
Eligibility Criteria
Inclusion
- 1\) Younger than 38 years old, basal serum level of follicle stimulating hormone \<10 IU / L; (2) Endometrium is less than 8mm in at least 2 cycles: superovulation cycle / natural cycle / estrogen replacement therapy / ovarian stimulation cycle; (3) at least 1 high quality frozen embryo; (4) There are no comorbidities that clearly affect pregnancy, such as adenomyosis, endometriosis, and intrauterine adhesions;
Exclusion
- abnormal karyotype;
- Accompanying other diseases of the uterus: uterine muscular wall myomas that affect the uterine cavity shape, more severe adenomyosis, severe endometriosis, congenital uterine malformations, endometrial tuberculosis, etc .;
- Contraindications to hormone replacement therapy;
- Participating in other clinical research;
- History of previous fundus diseases;
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2021
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04292886
Start Date
October 1 2019
End Date
November 30 2021
Last Update
March 3 2020
Active Locations (1)
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1
Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital
Nanjing, Jiangsu, China, 210008