Status:

UNKNOWN

Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery

Lead Sponsor:

Assiut University

Conditions:

Colorectal Cancer

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

Our aim will be to evaluate the efficacy of perioperative Duloxetine in decreasing acute postoperative pain after laparoscopic colorectal cancer surgery and its role in reducing postoperative morphine...

Detailed Description

Abdominal surgery is usually associated with severe; wide spread post-operative pain. The greater propensity for pain and opioid-related side effects are likely contributing factors for poor postsurgi...

Eligibility Criteria

Inclusion

  • ASA I-III
  • aged 18-65 years and scheduled for laparoscopic colorectal surgery for cancer colon

Exclusion

  • unable to express their pain or patient refusal.
  • allergy to the study drug
  • an abnormal liver or renal function tests
  • a chronic opioid abuser(\> 3 mo), being on chronic gabapentin or pregabalin(\> 3 mo)
  • antidepressant drugs, patients with psychiatric disorders
  • Pregnant females

Key Trial Info

Start Date :

March 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04294953

Start Date

March 1 2020

End Date

April 1 2021

Last Update

March 4 2020

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Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery | DecenTrialz