Status:
COMPLETED
Age-Related Effects of THC
Lead Sponsor:
University of Chicago
Conditions:
Tolerance
Adolescent Behavior
Eligibility:
All Genders
18-40 years
Phase:
EARLY_PHASE1
Brief Summary
Increased accessibility to cannabis and its primary psychoactive constituent THC has raised public health concerns. One major concern surrounds the potential risks associated with acute THC intoxicati...
Detailed Description
There is limited knowledge on the effects of THC in adolescents vs adults. One recent report compared responses to vaporized cannabis in heavy adolescent vs adult cannabis users and found that the ado...
Eligibility Criteria
Inclusion
- 18-20 years old OR 30-40 years old
- Body Mass Index 19-26
- High school education, fluent in English
- Occasional cannabis users ( 0 times in past 30 days AND used cannabis no more than 20 times in lifetime)
Exclusion
- History of daily cannabis use
- Past or present severe substance use disorder
- Current or past diagnosis with drug treatment for psychosis/bipolar/schizophrenia
- Cardiovascular illness, high blood pressure, abnormal electrocardiogram
- Current medications
- Pregnant or planning to become pregnant
Key Trial Info
Start Date :
March 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04294966
Start Date
March 10 2020
End Date
May 1 2021
Last Update
November 9 2023
Active Locations (2)
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1
University of Chicago Hospital
Chicago, Illinois, United States, 60637
2
University of Chicago
Chicago, Illinois, United States, 60637