Status:
UNKNOWN
Granisteron Versus Ondansetron for Prophylaxis Against Post-Spinal Anesthesia Shivering: a Randomized Controlled Study
Lead Sponsor:
Kasr El Aini Hospital
Conditions:
Spinal Anaesthetic
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
3\. Scientific committee approval (Was it scientifically approved by the department?) Yes Date of approval: Sunday ,1ST September,2019 Background and Rationale: Regional anesthesia is commonly asso...
Eligibility Criteria
Inclusion
- • With ASA physical status I and II
- Scheduled to undergo lower half surgery under spinal anesthesia such as lower limb orthopedic surgeries, lower limb plastic surgeries, or lower abdominal surgeries.
Exclusion
- • Patient refusal
- Patients with age above 60 years and below 18 years.
- Pregnant
- Patients with contraindications to spinal anesthesia
- Preoperative fever or hypothermia (temperature \>38°C or below 36.5°C), hypo or hyperthyroidism, a requirement for blood or blood product transfusion during surgery and medications likely to alter thermoregulation or nausea and vomiting, will be excluded.
- Patients with significant cardiopulmonary disease (i.e. ejection fraction \<40% and/or SpO2 \< 92% on room air) or psychological disorder
- impaired renal (serum creatinine \> 2 mg/dL) or hepatic function (class B or C on Child-Pugh score)
- Procedures with anticipated duration less than 90 minutes or more than 180 min, those received saddle block or those required vasodilator administration
- Allergy to any of the study drugs will be excluded from the study
Key Trial Info
Start Date :
April 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2020
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT04294992
Start Date
April 1 2020
End Date
September 1 2020
Last Update
March 4 2020
Active Locations (1)
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1
Kasr alainy medical school
Cairo, Egypt, 12566