Status:

COMPLETED

Clinical Performance and Reproducibility of the Accelerate PhenoTest™ Blood Culture (BC) Kit With New Antibiotic Wave I Updates

Lead Sponsor:

Accelerate Diagnostics, Inc.

Conditions:

Bacteremia

Eligibility:

All Genders

Brief Summary

This is a performance and reproducibility study to validate new or updated antimicrobials on the Accelerate PhenoTest™ BC kit. The data from this study will be used to support the submission to the FD...

Detailed Description

This clinical study entitled "Clinical Performance and Reproducibility of the Accelerate PhenoTest™ BC Kit Using the Accelerate Pheno™ System with New Antibiotic Wave I Updates for Antimicrobial Susce...

Eligibility Criteria

Inclusion

  • Blood culture positivity is ≤ 8 hours prior to initiation of testing with the Accelerate Pheno™ system
  • Positive blood culture sample containing gram-negative rods according to Gram stain results
  • For fresh specimens, de-identified, remnant positive blood culture specimens from patients for which Standard of Care (SOC) testing has been initiated and the remaining samples would otherwise be discarded
  • A minimum sample volume of 2.0 mL
  • Seeded blood culture specimens derived from archived bacterial

Exclusion

  • Blood culture positivity is \> 8 hours prior to initiation of testing with the Accelerate Pheno™ system
  • Insufficient (less than 2.0 mL) remnant sample volume
  • From a patient that has already been enrolled in the study
  • Fresh samples from Mycobacterial-type blood culture media (BACTEC™ Myco/F Lytic, BacT/ALERT® MP Bottle, VersaTREK® Myco) or charcoal-containing media
  • Seeded specimens that appear mixed (by Gram stain or purity plating) after bottle culture positivity

Key Trial Info

Start Date :

March 11 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 19 2022

Estimated Enrollment :

731 Patients enrolled

Trial Details

Trial ID

NCT04295915

Start Date

March 11 2020

End Date

April 19 2022

Last Update

April 22 2022

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Accelerate Diagnostics

Tucson, Arizona, United States, 85714

2

Penn State-Hershey Medical Center

Hershey, Pennsylvania, United States, 17033

3

Quest/med fusion

Lewisville, Texas, United States, 75067