Status:
COMPLETED
Biomarkers and SNP-polymorphisms in Post-infarction Cardiac Remodeling
Lead Sponsor:
Tomsk National Research Medical Center of the Russian Academy of Sciences
Conditions:
Myocardial Infarction
Eligibility:
All Genders
30-80 years
Brief Summary
The purpose of this study is to explore the serum levels of pro- and anti-inflammatory biomarkers and angiogenic growth factors and SNP polymorphisms of the promoter regions of their genes as well as ...
Detailed Description
The widespread introduction of modern methods of treatments of myocardial infarction in routine clinical practice has lead not only to a decrease in mortality, but also to an increase in the number of...
Eligibility Criteria
Inclusion
- Age ≥ 18 years at time of randomization
- Patients with acute coronary syndrome with ST segment elevation
- Signed informed consent to participate in the study
- Admission to the intensive care unit within 24 hours from the onset of the disease
- Coronary angiography within 24 hours of the onset of the disease
Exclusion
- Long persistent form of atrial fibrillation
- Valvular heart disease
- Shock of different genesis
- Multiple organ failure
- Chronic heart failure with a severe decrease in the left ventricular ejection fraction
- Sepsis
- Severe concomitant pathology
Key Trial Info
Start Date :
March 15 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04296253
Start Date
March 15 2019
End Date
September 30 2020
Last Update
October 6 2021
Active Locations (1)
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1
Cardiology Research Institute of Tomsk National Research Medical Center of the Russian Academy of Sciences
Tomsk, Tomskii Region, Russia, 634012