Status:

RECRUITING

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

Lead Sponsor:

Massachusetts General Hospital

Conditions:

Traumatic Brain Injury

Major Depressive Disorder

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have d...

Detailed Description

In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have d...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Male and female outpatients 18-65 years of age
  • A diagnosis of traumatic brain injury, major depressive disorder, bipolar disorder, schizophrenia, attention deficit hyperactivity disorder, borderline personality disorder and substance use disorders meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.
  • Exclusion Criteria
  • Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, shunts, pacemakers, pregnancy.
  • Active substance dependence (except for tobacco and cannabis).
  • Pregnant or nursing females.
  • Inability to participate in testing procedures.
  • Additional exclusion criteria for healthy controls:
  • Diagnosis of psychiatric of neurological disorder
  • Ongoing treatment with any psychotropic medications.

Exclusion

    Key Trial Info

    Start Date :

    September 1 2014

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    April 1 2026

    Estimated Enrollment :

    600 Patients enrolled

    Trial Details

    Trial ID

    NCT04296604

    Start Date

    September 1 2014

    End Date

    April 1 2026

    Last Update

    September 10 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Massachusetts General Hospital

    Boston, Massachusetts, United States, 02129