Status:
ACTIVE_NOT_RECRUITING
Preeclampsia Postpartum Antihypertensive Treatment
Lead Sponsor:
Medical College of Wisconsin
Conditions:
Preeclampsia
Hypertension in Pregnancy
Eligibility:
FEMALE
18+ years
Phase:
PHASE3
Brief Summary
The goal of this study is to compare whether antihypertensive treatment in the postpartum period decreases postpartum hypertension and its associated maternal morbidity, including risk of readmission ...
Detailed Description
This will be a randomized, controlled trial of 300 women with a diagnosis of preeclampsia at any point in their current pregnancy or immediately postpartum. Immediately postpartum is defined as preecl...
Eligibility Criteria
Inclusion
- Age \>= 18 years old
- Immediately postpartum (delivered in previous 96 hours)
- Diagnosed with preeclampsia during pregnancy, labor or immediately postpartum
- \>30% of blood pressures in the postpartum period were elevated (systolic 140 or higher OR diastolic 90 or higher)
Exclusion
- Chronic hypertension with superimposed preeclampsia
- Diagnosis of preeclampsia after discharge from delivery hospitalization
- Persistent severe range blood pressures after delivery requiring initiation of antihypertensive regimen by the care team
- \>50% of blood pressures in the postpartum period were normal (systolic less than 140 AND diastolic less than 90)
Key Trial Info
Start Date :
July 17 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04298034
Start Date
July 17 2020
End Date
December 30 2025
Last Update
October 23 2025
Active Locations (1)
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1
Medical College of Wisconsin-Froedtert Hospital
Milwaukee, Wisconsin, United States, 53226