Status:

COMPLETED

Nutrition Trial on the Glycaemic Response to High GI Meals Consumed at Morning vs. Evening-The ChroNu Study

Lead Sponsor:

Paderborn University

Collaborating Sponsors:

German Research Foundation

German Diabetes Center

Conditions:

Healthy

Eligibility:

All Genders

18-25 years

Phase:

NA

Brief Summary

Several studies suggest that meal timing plays an important role in the development of obesity and metabolic diseases. Especially in the evening, a high consumption of carbohydrates, which greatly inc...

Detailed Description

To address the hypothesis that dietary misalignment among young adults has detrimental short-term effects on glucose metabolism, participants will consume a meal rich in high GI carbohydrates on two s...

Eligibility Criteria

Inclusion

  • Healthy students of Paderborn University
  • 18 - 25 years old at time of screening for the ChroNu cohort
  • 18,5 kg/m² \< BMI \> 30 kg/m²
  • Free of diseases requiring constant or chronic medical treatment (except for oral contraceptives)
  • Willingness to participate in the nutrition trial (8 days) including invasive measurements
  • Fluent knowledge of the German language

Exclusion

  • students studying nutrition science at the University Paderborn
  • regular smokers
  • pregnancy or lactation
  • chronic diseases: diabetes mellitus (all types), pre-diabetes, individuals with bleeding disorders (thrombocytopenia, haemophilia)
  • contact dermatitis to adhesive plaster or skin disease that prevents the participant from wearing the CGM
  • intake of medication which influence the chronotype: such as antidepressants or sleeping pills
  • shift work in the past 3 months
  • crossing of \> 1-time zone in the past 3 months
  • strict vegetarians /vegans
  • individuals having an allergy or intolerance to food that is included in the diet

Key Trial Info

Start Date :

September 4 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 18 2020

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04298645

Start Date

September 4 2020

End Date

December 18 2020

Last Update

December 23 2020

Active Locations (1)

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Paderborn University

Paderborn, North Rhine-Westphalia, Germany, 33098