Status:
COMPLETED
THE EFFETCS OF NON-SURGICAL PERIODONTAL TREATMENT ON SALIVARY BIOMARKERS OF PATIENTS WITH OSTEOPOROSIS AND PERIODONTITIS
Lead Sponsor:
Gazi University
Conditions:
Osteoporosis
Periodontitis
Eligibility:
FEMALE
35-65 years
Phase:
NA
Brief Summary
Inflammatory mediators in periodontitis may lead to elevated systemic cytokine levels, resulting in increased bone resorption including the jaws. Osteoporosis may have an influence on the periodontal ...
Eligibility Criteria
Inclusion
- The participants were postmenopausal patients defined as absence of menstruation for at least 12 months.
- Patients with periodontitis;
- Patients who had no systemic diseases and were periodontally healthy (no attachment loss),
- Patients who were treated with oral bisphosphonate at least one year (70 mg tablet once weekly)
Exclusion
- if they had received any periodontal treatment in the preceding three months,
- if they were pregnant or in the period of lactation,
- if they had systemic diseases that may interfere with normal healing mechanism,
- if they had taken antibiotics, anticonvulsants, immunosuppressants, calcium channel blockers in the preceding six months.
- Smokers
Key Trial Info
Start Date :
June 30 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 30 2019
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT04299477
Start Date
June 30 2018
End Date
May 30 2019
Last Update
March 6 2020
Active Locations (1)
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1
Gazi University
Ankara, Cankaya, Turkey (Türkiye), 06500