Status:
RECRUITING
Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease
Lead Sponsor:
University of British Columbia
Conditions:
Interstitial Lung Disease
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Exercise training as part of a structured pulmonary rehabilitation program is a key factor in improving quality of life and symptoms in people with interstitial lung disease (ILD). Optimal methods of ...
Detailed Description
PURPOSE: The primary purpose of this study is to determine the effects of dietary nitrate supplementation on submaximal cycle exercise performance in patients with fibrotic ILD. HYPOTHESIS: Our pri...
Eligibility Criteria
Inclusion
- A multidisciplinary diagnosis of idiopathic pulmonary fibrosis (IPF), idiopathic fibrotic nonspecific interstitial pneumonia (NSIP), chronic hypersensitivity pneumonitis (HP), or unclassifiable ILD with a differential diagnosis that consists of the above diagnoses
- Fibrosis on high resolution computed tomography (HRCT): honeycombing, reticulation, or traction bronchiectasis
- Oxygen saturation ≥92% by pulse oximetry at rest while breathing room air
- Clinically stable for the preceding 6 weeks
- Can fluently read and write in English
Exclusion
- Contraindication to exercise testing (e.g. significant cardiovascular, musculoskeletal, neurological disease) (see Table 4 from ERS/ATS consensus statement)
- Other significant pulmonary or extra-pulmonary disease that, based on clinical assessment, could impair exercise capacity and/or oxygenation
- FVC \<50% or DLCO \<25%
- Use of prednisone \>10 mg/day for \>2 weeks within 3 months of the first study visit
- Cardiac pacemaker or any metal or electronics inside of the body
Key Trial Info
Start Date :
August 7 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04299945
Start Date
August 7 2024
End Date
December 31 2026
Last Update
January 15 2025
Active Locations (2)
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1
Providence Health Care - St. Paul's Hosptial
Vancouver, British Columbia, Canada, V6Z 1Y6
2
Vancouver Coastal Health
Vancouver, Canada, V5Z 1M9