Status:
COMPLETED
Mindfulness Based Stress Reduction and Post-Stroke Cognition
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
University of Maryland, College Park
National Institutes of Health (NIH)
Conditions:
Stroke
Stroke Sequelae
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
The investigators don't fully understand how, regardless of the size or location in the brain, minor strokes can result in significant problems with focus, attention, and multi-tasking that prevent in...
Detailed Description
Thrombectomy has significantly improved stroke outcomes. Nearly 80% of the investigators' clinic population now present with small strokes and low NIH Stroke Scale (NIHSS) scores. However, despite "go...
Eligibility Criteria
Inclusion
- Adults (≥18 years) presenting with neurological symptoms due to acute ischemic stroke (symptom onset within the week prior to admission).
- Evidence on brain MRI of acute ischemic stroke (imaging negative strokes and transient ischemic attacks (TIAs) will be excluded).
- Native English speaker (by self-report) prior to stroke.
- NIHSS \<8 at initial follow-up visit (approximately 30 days post-stroke).
- mRS 0-2 at initial follow-up visit.
Exclusion
- Primary intracerebral hemorrhage- as evidenced by blood on head CT or MRI.
- Presence of proximal large vessel occlusion.
- Cortical exam findings including aphasia or neglect.
- Prior history of dementia or undertreated psychiatric illness.
- Uncorrected hearing or visual loss.
- Inability to attend weekly MBSR or Stroke Support Group sessions.
- Inability to travel to College Park (UMD) for 2 MEG recording sessions.
- Presence of any of the following that would lead to significant artifact on MEG: cardiac pacemaker, intracranial clips, metal implants or external clips within 10mm of the head, metal implants in the eyes (unlikely given that all patients will have an MRI and criteria are similar).
- Claustrophobia, obesity, and/or any other reason leading to difficulty staying in the MEG machine for up to 1 hour.
Key Trial Info
Start Date :
January 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2023
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04302493
Start Date
January 1 2021
End Date
June 1 2023
Last Update
December 20 2024
Active Locations (1)
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1
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States, 21224