Status:
COMPLETED
Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS
Lead Sponsor:
Karachi Medical and Dental College
Conditions:
Coenzyme q10
Eligibility:
FEMALE
20-35 years
Phase:
PHASE4
Brief Summary
The study evaluates the effect of coenzyme q 10 on ovulation and subsequent pregnancy in women with polycystic ovarian syndrome. Half of the participants will receive coq10 and ovulation induction wit...
Eligibility Criteria
Inclusion
- Diagnosis of polycystic ovarian syndrome PCOS based on the revised 2003 consensus on diagnostic criteria and long-term health risks related to PCOS (2003).
- All women were previously treated with 100 mg of CC daily for 5 days per cycle, for two to three cycles with persistent anovulation or ovulate with very thin endometrium \<5 mm at the time of hCG administration
Exclusion
- Non-consenting.
- known autoimmune disorders
- prior treatment of endometriosis or surgery to reproductive tract
- prior history of pelvic inflammatory disease
- those with tubal factors and uterine factors as assessed on history and confirmed by normal hysterosalpingogram.
- Thyroid disorder as assessed by history examination and TSH level
- Patients with raised FSH
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2020
Estimated Enrollment :
149 Patients enrolled
Trial Details
Trial ID
NCT04302532
Start Date
July 1 2020
End Date
October 30 2020
Last Update
November 25 2020
Active Locations (1)
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1
Aziz medical center
Karachi, Sindh, Pakistan, 74600