Status:
COMPLETED
Use of Muscle Ultrasound to Predict Function
Lead Sponsor:
Tan Tock Seng Hospital
Conditions:
Spinal Cord Injury
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
Establish if change from the baseline in ultrasound muscle parameters over 2 months of rehabilitation correlates with functional status of SCI patients at the end of rehabilitation
Detailed Description
Rehabilitation is the key to ambulatory recovery in patients with spinal cord injury, although only 25% of patients regain this ability despite current rehabilitation protocols. There is emerging evid...
Eligibility Criteria
Inclusion
- First ever acute SCI
- Age 21-65 years
- Presence of weakness in the lower limbs (defined as either ASIA A, B, C or D)
- Independent in ambulation prior to onset of SCI
- Able to understand study procedures and sign informed consent
- Clinical suitability for rehabilitation
Exclusion
- Presence of premorbid lower musculoskeletal conditions eg contractures, fractures, previous operations, that prevents proper ultrasound assessment of the affected limb
- Cardiorespiratory conditions eg congestive cardiac failure (EF\<40%), chronic arrhythmias, COPD stage 3-4
- End stage illness, end stage renal failure, life expectancy \<6 months
- Other active neurological conditions
- Botulinum toxin injection over the past 3 months
Key Trial Info
Start Date :
February 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 30 2022
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04303728
Start Date
February 1 2020
End Date
January 30 2022
Last Update
April 28 2022
Active Locations (1)
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1
Tan Tock Seng Hospital Rehabilitation Centre
Singapore, Singapore, 569766