Status:

SUSPENDED

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study

Lead Sponsor:

University of Pittsburgh

Conditions:

Chronic Pancreatitis

Inflammatory Bowel Diseases

Eligibility:

All Genders

12+ years

Brief Summary

This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in t...

Detailed Description

The Genomic Resource to Enhance Available Therapies (GREAT1.0) Study is a research program for personalized medicine. It is a highly annotated genetic and biosample resource for multiple nested observ...

Eligibility Criteria

Inclusion

  • Case Subjects
  • Clinical diagnosis of a chronic disease or disorder (ex. pancreatitis, hepatitis or fatty liver, inflammatory bowel disease, irritable bowel syndrome, diarrhea, constipation, chronic pain syndromes, diabetes, hypertension, cardiovascular disease, chronic kidney disease, chronic neurologic disorders, rheumatological disorders, endocrine disorders, chronic pulmonary diseases, sinorespiratory disorders, chronic skin diseases, cancers and related disorders)
  • Ability to read and write in English;
  • Ability to provide informed consent
  • Control Subjects
  • • UPMC patients age 12 years without a chronic disorder.

Exclusion

  • Chronic infectious disease as the primary medical problem
  • Less than 12 years of age
  • Inability of the subject to understand the protocol
  • Inability to the subject provide informed consent

Key Trial Info

Start Date :

November 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

120000 Patients enrolled

Trial Details

Trial ID

NCT04306939

Start Date

November 1 2014

End Date

December 1 2026

Last Update

January 7 2026

Active Locations (1)

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University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213