Status:

UNKNOWN

The Influence of a New Implant Neck Configuration on Hard and Soft Tissue Healing

Lead Sponsor:

PerioCentrum Research

Conditions:

Implant Geometry, Osseointegration, Soft Tissue Volume, Marginal Bone Levels, Soft Tissue Recession, Volumetric Analysis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Title: Randomized Controlled Clinical Trial comparing two dental implants with different neck configurations. Objective: To evaluate the changes in peri-implant soft tissues and marginal bone level w...

Detailed Description

The study will be a prospective parallel randomized clinical trial (RCT) of approximately 20 months of duration, in which each patient will receive 1 implants placed in the posterior mandible. If the ...

Eligibility Criteria

Inclusion

  • Male or female ≥18 years old
  • Each patient will have one missing tooth in the posterior mandible (positions 4-6). There must be a natural tooth mesially and distally to the implant site. Free end situation are not allowed.
  • Adequate bone quality and quantity at the implant site to permit the insertion of a SWEDEN AND MARTINA® Prama Implant in the diameter of 4.25 mm and in the length of 8.5 mm, 10 mm or a Straumann Tissue Level in the diameter of 4.1 mm and in the length of 8 mm or 10mm.
  • Opposing dentition must be natural teeth or teeth/implant supported fixed restoration(s).
  • Patient has been informed of the follow-up visits and is willing to return to the clinical center for these follow-up visit.

Exclusion

  • These exclusion criteria might be systemic or local. In addition to the general contra-indication for dental implants the following exclusion criteria will be observed:
  • Systemic exclusion criteria:
  • Medical conditions requiring prolonged use of steroids and/or with medications that can interfere with bone metabolism
  • History of leukocyte dysfunction and deficiencies
  • History of neoplasic disease requiring the use of radiation or chemotherapy
  • Patients with history of renal failure
  • Patients with metabolic bone disorders such as osteoporosis
  • History of uncontrolled endocrine disorders
  • Physical handicaps that would interfere with the ability to perform adequate oral hygiene
  • Use of any investigational drug or device within the 30 day period immediately prior to implant surgery on study day 0
  • Alcoholism or drug abuse
  • History of immunodeficiency syndromes
  • Patients who smoke \>20 cigarettes per day or cigar equivalents.
  • Conditions or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance, unreliability
  • Local exclusion criteria:
  • Any bone augmentation on the implant site which was performed in the previous 3 months
  • Local inflammation, including untreated periodontitis
  • Mucosal diseases such as erosive lichen planus
  • History of local irradiation therapy
  • Presence of osseous lesions
  • Unhealed extraction sites (less than 6 weeks post extraction of teeth in intended sites)
  • Severe bruxing or clenching habits
  • Persistent intraoral infection
  • Exclusion criteria at surgery:
  • Lack of primary stability of implant.
  • Presence of vertical dehiscence
  • Unable to place the implant according to the prosthetic requirements. In any of these instances the patient will not be included in the study and a new patient will be recruited and randomized.

Key Trial Info

Start Date :

June 17 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 17 2021

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT04308083

Start Date

June 17 2019

End Date

March 17 2021

Last Update

March 13 2020

Active Locations (1)

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1

PerioCentrum Madrid

Madrid, Spain, 28020