Status:
COMPLETED
Cortical Enhancement of Posture, Movement Planning, and Execution of Upright Reaching Following Stroke
Lead Sponsor:
University of Maryland, Baltimore
Conditions:
Stroke
Upper Extremity Paresis
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
Stroke is the leading cause of disability and diminished quality of living that frequently includes impairments of postural control and upper extremity (UE) function. The interaction of posture and UE...
Eligibility Criteria
Inclusion
- Inclusion Criteria for stroke:
- Unilateral cortical or white matter subcortical stroke
- Age 40 yrs and older
- ≥ 6 months post ischemic stroke or ≥ 12 months post hemorrhagic stroke
- Residual arm hemiparesis as indicated by Fugl-Meyer Upper Extremity score between 20-65
- Having the ability to perform reaching movements with the paretic arm in standing without an assistive device.
- Exclusion Criteria for stroke:
- Stroke involving bilateral hemisphere, brainstem or cerebellum
- Any medical condition precluding participation in testing
- Other health conditions affecting balance and upper extremity movement function beyond the effects of stroke.
- Inclusion Criteria for healthy controls:
- Age-matched to the stroke subjects
- Without a history of stroke or any known neurological conditions
- Having the cognitive ability to follow two-step commands and give informed consent
- Exclusion Criteria for healthy controls:
- Any medical condition precluding participation in testing
- Other health conditions affecting balance and upper extremity movement function beyond the effects of stroke.
- Participants were also excluded if they did not meet the TMS safety criterion including having implantable medical devices, history of seizures, taking medications to reduce anxiety, sedatives, and seizure, and pregnancy.
Exclusion
Key Trial Info
Start Date :
October 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2017
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04308629
Start Date
October 1 2016
End Date
October 30 2017
Last Update
March 16 2020
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