Status:
COMPLETED
Constipation, Gut Microbiome, and Microbial-derived Uremic Toxins From the Gut Microbiota in HD Patients
Lead Sponsor:
Tungs' Taichung Metroharbour Hospital
Conditions:
Constipation
Inflammation
Eligibility:
All Genders
20-90 years
Brief Summary
Chronic constipation is a prevalent, multifactorial gastrointestinal disorder, and its etiology and pathophysiology remain poorly understood. Recently studies using 16S rDNA-based microbiota profiling...
Detailed Description
Study Design and Population Patients and Methods This study will include 90 dialysis patients. Patients over age 20 years old and undergoing HD for at least 6 months will be enrolled. Patients with ...
Eligibility Criteria
Inclusion
- Patients over age 20 years old
- Undergoing hemodialysis (HD) for at least 6 months
Exclusion
- Inflammatory diseases
- Cancer
- AIDS
- Autoimmune disease
- Use of a central catheter for hemodialysis access
- Amputated limbs
- Pregnancy
- Using catabolic drugs
- Using antioxidant vitamin supplements
- Using symbiotic and antibiotics
Key Trial Info
Start Date :
March 10 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT04309019
Start Date
March 10 2020
End Date
December 31 2020
Last Update
April 29 2022
Active Locations (1)
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1
Tungs' Taichung MetroHarbour Hospital
Taichung, Taiwan