Status:

COMPLETED

Description of the Analgesia Obtained With the Anesthesiological Protocols Currently Used in Breast Surgery

Lead Sponsor:

Careggi Hospital

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

This study aims to describe the pain-relieving effect obtained with the current post-surgery pain control methods used in breast surgery by measuring the painful sensation and the consumption of opioi...

Detailed Description

Breast cancer is the second most common in the world and the most frequent in the female population. In Italy, around 48,000 new cases were diagnosed in 2013. Every year patients undergoing surgical p...

Eligibility Criteria

Inclusion

  • Female gender
  • Age\> 18 years;
  • Patients in ASA class \<4;
  • Planned mastectomy surgery, simple mastectomy with immediate reconstruction, mastectomy with sentinel-lymph node biopsy, modified radical mastectomy (unilateral or bilateral);
  • Absence of allergies or hypersensitivity reported and / or documented to drugs used routinely for post-operative analgesia;
  • Absence of inflammatory changes at the surgical site level;
  • Presence of the patient's informed consent to the processing of personal data;

Exclusion

  • Known alterations of coagulation;
  • Known cardiac arrhythmias (atrial sinus block I, II, III type, atrioventricular block I, II and III type);
  • Documented renal failure (patient undergoing renal replacement therapy, or creatininemia ≥ 2 mg / dl);
  • Severe hepatic insufficiency (Child-Plugh class III and IV); Seizure states (absences, seizures of large and / or small epileptic disease);
  • Respiratory failure (PaO2 ≤ 60mmHg PaCO2≥ 50mmHg);

Key Trial Info

Start Date :

September 12 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 31 2018

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04309929

Start Date

September 12 2016

End Date

July 31 2018

Last Update

March 17 2020

Active Locations (1)

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Azienda Ospedaliero Universitaria Careggi

Florence, Italy, 50100