Status:
RECRUITING
Long-term Prognosis of Patients With Hepatitis B Related Acute-on-chronic Liver Failure
Lead Sponsor:
Third Affiliated Hospital, Sun Yat-Sen University
Conditions:
Hepatitis B
Acute-On-Chronic Liver Failure
Eligibility:
All Genders
18-65 years
Brief Summary
This study is to investigate the long-term outcomes and prognostic risk factors in patients recovered from hepatitis B virus related acute on-chronic liver failure.
Detailed Description
Chronic acute liver failure (ACLF) is a systemic multi-organ failure driven by acute liver injury in the basis of chronic liver disease. The main cause of chronic acute liver failure in China is hepat...
Eligibility Criteria
Inclusion
- Age from 18 to 65 years old;
- The diagnosis consistent with hepatitis b associated chronic acute liver failure；
- After hospitalization, the survival time \> 90 days；
- The inpatient clinical data are complete.
Exclusion
- Human immunodeficiency virus infection or congenital immune deficiency diseases;
- Liver cancer and other tumors, autoimmune liver disease, genetic and metabolic liver disease, or other serious diseases that significantly affect patient survival;
- Other conditions that the researchers judged not appropriate for inclusion.
Key Trial Info
Start Date :
May 15 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04310787
Start Date
May 15 2020
End Date
December 31 2024
Last Update
November 29 2024
Active Locations (1)
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1
Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China, 510630