Status:
COMPLETED
Ventilatory Strategy for the Prevention of Atelectasis During Bronchoscopy Under General Anesthesia, VESPA Trial
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Lung Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This trial compares two different types of ventilation for the prevention of partial or complete collapsed lung (atelectasis) in patients undergoing bronchoscopy under general anesthesia. Ventilatory ...
Detailed Description
PRIMARY OBJECTIVE: I. To determine if our ventilatory strategy to prevent atelectasis (VESPA) can reduce the intra-procedural development of atelectasis during bronchoscopy under general anesthesia w...
Eligibility Criteria
Inclusion
- Adult patients undergoing bronchoscopy with radial probe endobronchial ultrasound (RP-EBUS) for peripheral lung lesions
- Recent (\< 4 weeks) chest computed tomography (CT) performed prior to the bronchoscopy
- Voluntary informed consent to participate in the study
Exclusion
- Patients with baseline lung consolidation, interstitial changes or lung masses (\> 3 cm in diameter) in dependent areas of the lung (right/left \[R/L\] B6, 9, or 10 bronchial segments) as seen on most recent CT
- Pregnancy
- Ascites
- Known diaphragmatic paralysis
- Air-trapping with residual volume \> 150% of predicted
- History of primary or secondary spontaneous pneumothorax
- Lung bullae \> 5 cm
Key Trial Info
Start Date :
May 27 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 21 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04311723
Start Date
May 27 2020
End Date
March 21 2024
Last Update
October 22 2024
Active Locations (1)
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1
M D Anderson Cancer Center
Houston, Texas, United States, 77030