Status:

COMPLETED

A Study of Infliximab in the Treatment of Chinese Children With Crohn's Disease

Lead Sponsor:

Johnson & Johnson (China) Investment Ltd.

Conditions:

Crohn Disease

Eligibility:

All Genders

6-17 years

Brief Summary

The main purpose of this study is to record the use of Infliximab (IFX) in the treatment of Chinese children with Crohn's disease (CD) in routine clinical practice and to summarize the clinical effica...

Eligibility Criteria

Inclusion

  • Must have a confirmed diagnosis of Crohn's disease
  • Must sign, and their legal guardians/legally-acceptable representative where applicable must sign, a participation agreement/ICF allowing data collection and source data verification in accordance with local requirements
  • First-time received IFX treatment

Exclusion

  • History of medical contraindications for Infliximab (IFX), example. serious infections, active tuberculosis (TB), lymphoma and other malignancies, moderate to severe heart failure, hypersensitivity to inactive components of the product or to any murine proteins
  • Previous exposure to Infliximab or any other biologics
  • Received an investigational drug (including investigational vaccines) or used an invasive investigational medical device within 90 days before the start of the study or the first data collection time point
  • Currently enrolled in an investigational study
  • Have other Crohn's-like disease that are associated with mono-genetic immune disorders

Key Trial Info

Start Date :

July 15 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 12 2023

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT04312659

Start Date

July 15 2020

End Date

September 12 2023

Last Update

April 27 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Guangzhou Women And Children's Medical Center

Guangzhou, China, 510623

2

The Childrens Hospital Zhejiang University School Of Medicine

Hangzhou, China, 310052

3

Ruijin Hospital Shanghai Jiao Tong University

Shanghai, China, 200025

4

Children's Hospital of Fudan University

Shanghai, China, 201102