Status:

TERMINATED

Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease

Lead Sponsor:

Tangible Science

Collaborating Sponsors:

Boston Sight

Conditions:

Stevens-Johnson Syndrome

Graft Versus Host Disease in Eye

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this research is to determine if the Tangible Boost system adequately replenishes the Hydra-PEG coating on the surface of a rigid contact lens. Hydra-PEG is a coating for soft and rigid c...

Eligibility Criteria

Inclusion

  • Written Informed Consent has been obtained prior to any study-related procedures taking place
  • Written documentation has been obtained in accordance with the relevant county and local privacy requirements, where applicable
  • Male or female
  • 18 years of age and older prior to the initial visit
  • Is a new or established wearer of PROSE lenses with optimized lens fit prior to enrollment in the study
  • Has been diagnosed with Dry Eye Syndrome, SJS, SS, or GVHD
  • In the opinion of the investigator, the subject has the ability to follow study instructions
  • In the opinion of the investigator, the subject has the ability to complete all study procedures and visits

Exclusion

  • aphakic (i.e., missing their natural lens inside the eye)
  • Is currently participating in any other type of eye-related clinical or research study
  • Is pregnant or nursing as reported by the subject
  • Has a condition or is in a situation which, in the investigator's opinion, may put the subject at significant risk, may confound study outcomes, or may significantly interfere with the subject's participation in the study.
  • Has a known and self-reported allergy to the following substances: polyethylene glycol, polyvinyl alcohol, triethanolamine, polyquaternium-1, or edetate disodium, which are components of the Tangible Boost and Hydra-PEG systems or care regimen.
  • Has had previous ocular surgery within the past 12 weeks
  • Adults unable to consent (including adults unable to read and understand English)
  • Individuals who are not yet adults (infants, children, teenagers)
  • Pregnant women
  • Prisoners
  • Employees of BostonSight

Key Trial Info

Start Date :

February 24 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 21 2023

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT04313725

Start Date

February 24 2020

End Date

June 21 2023

Last Update

September 16 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Boston Sight

Needham, Massachusetts, United States, 02494

Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease | DecenTrialz