Status:
UNKNOWN
Comparison of Analgesic Effect and Prognosis of Butorphanol and Fentanyl in Patients With Mechanical Ventilation
Lead Sponsor:
Jiangsu Hengrui Pharmaceutical Co., Ltd.
Conditions:
Analgesia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
ICU patients often in a strong stress environment. Various invasive procedures such as wound dressing change, sputum suction,Pull out the thoracic duct etc. At the same time, the diseases and environm...
Detailed Description
For enrolled patients, the investigators required that inclusion criteria were informed consent signed.The exclusion criteria were described in detail in the CRF standard. The recruitment of patients ...
Eligibility Criteria
Inclusion
- aged \>= 18 years, 18kg / m2 \< BMI \< 30 kg / m2;
- patients with invasive mechanical ventilation (refer to the clinical application guide of mechanical ventilation \[2006\];
- the expected ventilation time was \>= 24h, and the ventilation time was \< 48h;
- sign the informed consent voluntarily and participate in the research. -
Exclusion
- known allergy to any study drug;
- for chronic pain of grade 3 or above in the World Health Organization, strong opioids, such as morphine, are often used. Recently, opioids are used for analgesia through spinal cord catheter, epidural or any other regional block;
- the American Society of anesthesiologists (ASA) classified the fifth grade patients (on the verge of death);
- nerve injury or brain organic pathological changes;
- participate in clinical research in the past 30 days;
- pregnancy or lactation;
- the researcher thinks it is not suitable to participate in the clinical trial.
Key Trial Info
Start Date :
December 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
355 Patients enrolled
Trial Details
Trial ID
NCT04315935
Start Date
December 15 2019
End Date
December 31 2021
Last Update
March 20 2020
Active Locations (1)
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1
Hebei People's Hospital
Hebei, Hebei, China