Status:

COMPLETED

Study to Evaluate Changes in Cognitive Function in Patients Treated With PCSK9 Inhibitors

Lead Sponsor:

Jose Seijas Amigo

Conditions:

Cognitive Function

Hypercholesterolemia

Eligibility:

All Genders

18+ years

Brief Summary

The main objective will be to evaluate the changes in the cognitive function in naive patients treated with PCSK9 inhibitors (Alirocumab and Evolocumab) by using the Montreal Cognitive Assesment quest...

Eligibility Criteria

Inclusion

  • Patients 18 years old or over
  • To start with the first funded dose of PCSK9 inhibitors ( LDL \> 100 mg/dL)
  • Maximum dose or statin intolerance

Exclusion

  • Diagnosis of any disease related with cognitive deterioration

Key Trial Info

Start Date :

March 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 13 2023

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT04319081

Start Date

March 1 2020

End Date

January 13 2023

Last Update

January 17 2023

Active Locations (12)

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Page 1 of 3 (12 locations)

1

Hospital de Virxen da Xunqueira de Cee

Cee, A Coruña, Spain

2

Hospital Arquiteto Marcide de Ferrol

Ferrol, A Coruña, Spain

3

Hospital del Barbanza

Ribeira, A Coruña, Spain

4

Hospital Clínico Universitario de Santiago de Compostela

Santiago de Compostela, A Coruña, Spain