Status:
UNKNOWN
Continuous Passive Paracentesis for Intra-abdominal Hypertension
Lead Sponsor:
Centro Hospitalar de Lisboa Central
Collaborating Sponsors:
NOVA Medical School
Conditions:
Ascites Hepatic
Cirrhosis, Liver
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Liver cirrhosis patients in Intensive Care present intra-abdominal hypertension and this is an independent risk factor for increased organ disfunction and mortality. Patients will be randomized into ...
Detailed Description
Intra-abdominal hypertension is an independent risk factors for increased mortality in Intensive Care patients and is highly prevalent in the critically ill cirrhotic patient. This study compares two ...
Eligibility Criteria
Inclusion
- liver cirrhosis diagnosis with ascites
- ICU admission for medical reason
Exclusion
- prior liver transplant
- haemorrhagic ascites
- extreme severity: CLIF-SOFA number of organ failures 5 or more
- less than 24 hours of ICU stay
- Any of the following conditions at 24 hours of ICU stay:
- i. Hemorrhagic shock with active uncontrolled bleeding ii. Refractory shock (MAP\<60mmHg) with multiple vasopressors iii. Predictably short ICU stay (\<72 hours) iv. Therapeutic futility determined by the medical staff
Key Trial Info
Start Date :
November 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04322201
Start Date
November 2 2019
End Date
May 31 2022
Last Update
March 26 2020
Active Locations (1)
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1
UCIP7 - Centro Hospitalar Universitário de Lisboa Central
Lisbon, Portugal, 1050-099