Status:

UNKNOWN

Thyroid Dysfunction in Patients With Nephrotic Syndrome

Lead Sponsor:

Merna Makram

Collaborating Sponsors:

Assiut University

Conditions:

Thyroid Dysfunction

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

This study is to evaluate Thyroid Hormone profile in patients with Nephrotic syndrome to identify clinical predictor of Thyroid dysfunction in patients with Nephrotic syndrome

Detailed Description

Nephrotic syndrome (NS) is one of the most popular glomerular diseases all over the world It result in loss of various macromolecules which exist in the plasma and bound to plasma proteins. They are c...

Eligibility Criteria

Inclusion

  • Nephrotic syndrome defined by the following:
  • Generalized edema
  • Urine protein excretion \> 3,5 g/24 hours
  • Urine protein to creatinine ratio \> 3,500mg/g
  • Serum albumin level less than 30 g/L

Exclusion

  • \- 1) Patients \< 18 years old 2) Patients who have Thyroid diseases, current or past history of thyroid hormone or antithyroid drug intake.
  • 3\) Patients who have diabetes mellitus or autoimmune diseases as systemic lupus erythematosus and RA 4) Medications known to affect thyroid function. 5) Patients with liver cirrhosis and chronic liver disease as augmentin

Key Trial Info

Start Date :

October 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04323007

Start Date

October 1 2020

End Date

October 1 2022

Last Update

March 26 2020

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