Status:

COMPLETED

Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal Cancer

Lead Sponsor:

Institut Cancerologie de l'Ouest

Conditions:

Rectal Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This trial is assessing how Bladder filling variations and thus mesorectal movements are less when radiotherapy treatment is received with an empty bladder in rectal cancer

Detailed Description

The purpose of this study is to show that the variations of bladder volume and mesorectal movements are less with empty versus filled bladder in rectal cancer. In this study, patient will be treated ...

Eligibility Criteria

Inclusion

  • Histologically confirmed rectal adenocarcinoma
  • T2 N+ or T3 any N, eligible for radiotherapy or neo-adjuvant radio-chemotherapy treatment in a long course of 25 fractions
  • Performance Status less or equal to 2
  • Male or female 18 Years and older
  • Creatinine clearance greater than or equal to 50ml/min
  • Fertile patients must use effective contraception
  • Written informed consent
  • Patient must be affiliated to a Social Health Insurance

Exclusion

  • Previous treatment with pelvic radiotherapy
  • Chronic inflammatory bowel disease in flare-up.
  • Urinary catheterization, urinary diversion or cystectomy
  • Hip prosthesis
  • History of prostatectomy, or hysterectomy
  • Urinary incontinence \> 2
  • Pregnant or nursing patient
  • Persons deprived of their liberty, as well as adults subject to a legal protection measure
  • Impossibility to submit to the medical follow-up of this clinical trial for geographical, social or psychological reasons

Key Trial Info

Start Date :

September 8 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 11 2024

Estimated Enrollment :

63 Patients enrolled

Trial Details

Trial ID

NCT04323722

Start Date

September 8 2020

End Date

September 11 2024

Last Update

November 7 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Institut de Cacerologie de l'ouest - site Paul Papin

Angers, France, 49055

2

ICO René Gauducheau

Saint-Herblain, France, 44805