Status:
COMPLETED
Effect of the Type and Emulsification of Dietary Fat on the Carotenoids Absorption
Lead Sponsor:
National University of Singapore
Collaborating Sponsors:
Singapore Institute of Food and Biotechnology Innovation
Conditions:
Carotenoids
Eligibility:
All Genders
19-45 years
Phase:
NA
Brief Summary
This study is designed to assess the effects of 1) the emulsification 2) the type of dietary fat on carotenoid (CAT) absorption employing an in-vitro digestion system (Proof of Concept) and well-desig...
Detailed Description
In all, twenty-five healthy men and women (aged =19 and =45 y, approximately half men and half women, with the expectation that = 20 subjects will complete the study (= 20 % dropout rate)) will be rec...
Eligibility Criteria
Inclusion
- Ability to give an informed consent
- Age 19 to 45 years
- Willing to follow the study procedures
Exclusion
- Significant weight change \> 3 kg in the past 3 months;
- Exercising vigorously over the past 3 months (\*Defined as having \> 6 metabolic equivalents of exercise daily; approximately 20 mins of moderate intensity exercise (e.g. slow jogging);
- Intestinal disorders including lipid malabsorption;
- Diabetes or prediabetes (fasting blood glucose \> 100 mg/dL);
- Smoking;
- Drinking more than 2 alcoholic drinks per day;
- Taking lipid-lowering medications or dietary supplements affecting plasma lipid-lipoprotein concentration.
- Menopausal women, those using hormone based contraceptives, those having abnormal menstrual cycles, and those who are pregnant, lactating or planning to become pregnant.
- Following any restricted diet (e.g. vegetarian)
- Taking dietary supplements which may impact the outcome of interests (e.g. carotenoids supp.)
- Insufficient venous access to allow the blood collection
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2021
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT04323826
Start Date
April 1 2021
End Date
September 1 2021
Last Update
September 10 2021
Active Locations (2)
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1
Department of Food Science and Technology; National University of Singapore
Singapore, Singapore, 117546
2
Investigational Medical Unit (IMU)
Singapore, Singapore, 117599