Status:

COMPLETED

Aftereffects and Reliability of Two Homeostatic Plasticity Induction Protocols

Lead Sponsor:

Aalborg University

Conditions:

Healthy

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

People suffering from chronic pain exhibit changes in the way the central nervous system processes pain. Some of the changes in the central nervous system are associated with how the brain adapts to t...

Detailed Description

The aim of this study is to investigate the corticomotor excitability changes provoked by two homeostatic plasticity induction protocols, specifically the duration and the test-retest reliability of s...

Eligibility Criteria

Inclusion

  • Healthy, aged between 18-60 years, right-handed and can speak and understand English.

Exclusion

  • Lack of ability to cooperate
  • History or present chronic pain or current acute pain
  • Pregnancy
  • Drug addiction defined as the use of cannabis, opioids or other drugs
  • Present and previous neurological disorders such as epilepsy, Alzheimer's disease, dementia, stroke, migraine and other headache disorders, multiple sclerosis, Parkinson's disease, neuroinfections, brain tumors and head trauma.
  • Present or previous musculoskeletal disorders such as tendonitis, degenerative disc disease, mechanical back syndrome, and ruptured/herniated disc.
  • Present or previous mental illnesses such as depression, bipolar disorder, and schizophrenia.
  • Current use of medications that may affect the trial (e.g. analgesics, anti-inflammatories, anti-depressives)
  • Contraindications to TMS application (history of epilepsy, metal implants in head or jaw, etc.)
  • Failure to pass the tDCS screening questionnaire
  • Failure to pass the "TASS questionnaire"

Key Trial Info

Start Date :

January 15 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 9 2020

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04324801

Start Date

January 15 2020

End Date

June 9 2020

Last Update

October 8 2020

Active Locations (1)

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Aalborg University

Aalborg, Denmark, 9220

Aftereffects and Reliability of Two Homeostatic Plasticity Induction Protocols | DecenTrialz