Status:

UNKNOWN

Reduction of Trauma-induced Intrusions and Amygdala Hyperreactivity Via Non-invasive Brain Stimulation

Lead Sponsor:

University Hospital, Bonn

Conditions:

Intrusive Thoughts

Post Traumatic Stress Disorder

Eligibility:

All Genders

18-45 years

Phase:

NA

Brief Summary

The study will focus on the modulation of intrusive memories via functional magnetic resonance imaging (fMRI)-guided repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex ...

Detailed Description

Traumatic experiences can lead to posttraumatic stress disorder (PTSD) with clinical manifestations including intrusions, avoidance behavior, and hyperarousal. Unlike most other psychological disorder...

Eligibility Criteria

Inclusion

  • Healthy subjects

Exclusion

  • current psychiatric illness
  • current psychiatric medication or psychotherapy
  • past PTSD diagnosis
  • MRI contraindication (e.g. metal in body, claustrophobia)
  • pregnancy

Key Trial Info

Start Date :

July 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 30 2020

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT04325087

Start Date

July 1 2019

End Date

May 30 2020

Last Update

March 27 2020

Active Locations (1)

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Department of Psychiatry, University of Bonn

Bonn, Germany, 53105