Status:
COMPLETED
Mycoprotein as the Basis of a Sustainable Diet to Support Muscle Mass Maintenance and Reconditioning in Older Adults.
Lead Sponsor:
University of Exeter
Conditions:
Aging
Sarcopenia
Eligibility:
All Genders
55-75 years
Phase:
NA
Brief Summary
A hallmark of ageing is loss of skeletal muscle mass and strength (sarcopenia). Sarcopenia is explained, partially, by reduced responsiveness of muscle to dietary protein. This 'anabolic resistance' c...
Detailed Description
Dietary protein plays a critical role in the daily regulation of muscle mass by virtue of its ability to regularly stimulate muscle protein synthesis rates. Sarcopenia is mechanistically explained, at...
Eligibility Criteria
Inclusion
- Body mass index between 18 and 30
- Recreationally active
Exclusion
- Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes) (as this may affect normal protein metabolism).
- Any diagnosed cardiovascular disease or hypertension.
- Elevated blood pressure at the time of screening. (An average systolic blood pressure reading of ≥150mmHg over two or more measurements and an average diastolic blood pressure of ≥90mmHg over two or more measurements.)
- Chronic use of statins or diabetic medication.
- A personal or family history of epilepsy, seizures or schizophrenia.
- Allergic to mycoprotein / Quorn, penicillin, or milk.
Key Trial Info
Start Date :
March 22 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2020
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT04325178
Start Date
March 22 2018
End Date
January 31 2020
Last Update
March 27 2020
Active Locations (1)
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1
University of Exeter
Exeter, Devon, United Kingdom, EX1 2LU