Status:
COMPLETED
CADDIE Trial - Computer Aided Diagnosis and Detection for Intelligent Endoscopy
Lead Sponsor:
University College, London
Conditions:
Polyps
Adenoma Colon
Eligibility:
All Genders
18+ years
Brief Summary
Background: Colonoscopy is accepted to be the gold standard for screening of colorectal cancer (CRC). Most CRCs develop from adenomatous polyps, with colonoscopy accepted to be the gold standard for ...
Eligibility Criteria
Inclusion
- Patient's scheduled to undergo a surveillance or symptomatic colonoscopy with an endoscopist participating in the study phase of the trial.
- Male and female participants aged 18 years or older at the time of informed consent.
- Patient's able to comprehend, sign and date the written informed consent document to participate in the study.
Exclusion
- Emergency colonoscopies and/or inpatient colonoscopies.
- Patients with inflammatory bowel disease (IBD)
- Patients with Colorectal Cancer (CRC)
- Patients with previous CRC
- Patients with previous colonic resection
- Patients returning for a planned elective therapeutic colonoscopy.
- Polyposis syndromes
- Current or relevant history of a physical or psychiatric illness or any medical condition that in the opinion of the investigator could affect the patient's safety or interfere with the study assessments
- Patients with a contraindication for biopsy or polypectomy. These include:
- Patients who have not withheld medications pre-disposing to bleeding at time of colonoscopy as per local site /national guidelines 30.
- Patients with a history of haemostasis disorders (Haemostasis disorders will include but will not be limited to: patients with haemophilia or other congenitally acquired clotting factor deficiencies, patients with cirrhosis with coagulopathy, patients known to have thrombocytopenia (\<80,000 platelet/ul) and individuals with Von Willebrand's disease or other known platelet malfunction disorders).
- Patients is enrolled in another research study with an investigational medicinal product (IMP) or non-IMP that pre-disposes them to bleeding
Key Trial Info
Start Date :
April 29 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 8 2023
Estimated Enrollment :
739 Patients enrolled
Trial Details
Trial ID
NCT04325815
Start Date
April 29 2021
End Date
March 8 2023
Last Update
February 19 2025
Active Locations (1)
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1
University College London
London, United Kingdom