Status:

UNKNOWN

Immunopathological Analysis in a French National Cohort of Membranous Nephropathy

Lead Sponsor:

Centre Hospitalier Universitaire de Nice

Conditions:

Membranous Nephropathy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

National cohort of all cases of membranous nephropathy (MN) during a 1 year period in France, based on a pathological and/or serological diagnostic, collecting the data on: * incidence of MN * preval...

Detailed Description

Membranous nephropathy is a rare auto-immune disease, yet a major cause of nephrotic syndrome in adults. It is characterised by the deposition of antigen-antibody complexes on the glomerular basement ...

Eligibility Criteria

Inclusion

  • Age 18 years or more
  • Biopsy on a native kidney consistent with MN and/or positivity for serum anti-PLA2R1 and/or anti-THSD7A antibodies
  • Signed informed consent

Exclusion

  • Diagnosis error based on the kidney biopsy staining or on serology analyses for the positivity for anti-PLA2R1 and/or anti-THSD7A
  • Patients unable to give an informed consent
  • Patients withdrawing an informed consent

Key Trial Info

Start Date :

July 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2024

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT04326218

Start Date

July 1 2020

End Date

July 1 2024

Last Update

April 7 2020

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