Status:
UNKNOWN
Evolution of Multiple Primary Lung Cancer (Evolution)
Lead Sponsor:
Peking University People's Hospital
Collaborating Sponsors:
Guangzhou Burning Rock Medical Examination Institute Co., Ltd.
Conditions:
Multiple Primary Lung Cancers
Lung Cancer
Eligibility:
All Genders
18-80 years
Brief Summary
To investigate the evolutionary genomic landscape, explore the genetic tumor heterogeneity and microenvironment of multiple primary lung cancer (MPLC) by using tissue genetic analysis and circulating ...
Detailed Description
Multiple primary lung cancer (MPLC) has become a worldwide problem due to the difficulty in diagnosis, treatment and surveillance. Although exploring tumour clonal heterogeneity and microenvironment c...
Eligibility Criteria
Inclusion
- Aged 18 to 80 years
- Patients who are clinically diagnosed multiple lung cancers, and undergo surgical treatment.
- No history of any malignancy in recent 5 years.
- No chemotherapy, radiotherapy or targeted therapy will be performed before surgery.
- Surgical removal of at least 2 tumors confirmed to be lung cancer postoperatively by pathologic evaluation.
Exclusion
- All lesions present as pure ground-glass opacities (GGOs) on CT scans.
- Patients who do not undergo R0 resection (including tumors located bilaterally but only unilaterally resected).
- Unqualified blood samples.
- Unable to comply with the study procedure
Key Trial Info
Start Date :
January 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04326751
Start Date
January 1 2021
End Date
December 31 2023
Last Update
March 30 2020
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