Status:
COMPLETED
RCT Mesenchymal Stem Cells Versus Hyaluronic Acid in OA Knee):
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Osteoarthritis, Knee
Eligibility:
All Genders
18-65 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this study is to evaluate the therapeutic effect of adult autologous mesenchymal stem cells (abbreviated as MSCs) in patients with osteoarthritic knee and compare to intra articular inj...
Detailed Description
Study Participants: This study will involve patients affected by osteoarthritis who comply with the inclusion and exclusion criteria. 30 patients, between the age of 18 and \<65, will be enrolled in ...
Eligibility Criteria
Inclusion
- Male and female subjects aged between 18 and \< 65
- Radiological evidence of osteoarthritis with Kellgren and Lawrence grade 2 and 3
- Patients on a pain level equal to or higher than 5 on a VAS scale of 10
Exclusion
- Previous cases of alcoholism or drug abuse
- Pregnancy and breast-feeding
- Serious pathologies such as carcinoma or autoimmune disease
- Hypersensitivity toward Hyaluorinc Acid
- Undergoing steroid-based systemic therapy or interrupted since less than 1 month
- Significant hematologic diseases
- Mechanical instability, ligamentous laxity/deficiency or gross deformity
Key Trial Info
Start Date :
January 31 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04326985
Start Date
January 31 2015
End Date
February 28 2019
Last Update
May 18 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Orthopaedics & Traumatology
Hong Kong, Hong Kong