Status:
RECRUITING
The Allergen Reduction and Child Health Study (ARCHS)
Lead Sponsor:
Tulane University
Collaborating Sponsors:
Patient-Centered Outcomes Research Institute
Conditions:
Asthma in Children
Eligibility:
All Genders
5-17 years
Phase:
NA
Brief Summary
The Allergen Reduction and Child Health Study (ARCHS) is a 12-month, two group randomized control trial of children with asthma and who are exposed to cockroaches. Children ages 5 - 17 living in the G...
Detailed Description
Background and Significance: Asthma is a serious, complex, and highly prevalent childhood respiratory disorder leading to inflammation and narrowing of the airways. If uncontrolled it negatively impac...
Eligibility Criteria
Inclusion
- Age 5 - 17 years; with uncontrolled persistent asthma defined as the child experiencing at least one of the following: one overnight hospitalization for asthma within the past six months OR two unscheduled clinic or emergency department visits for asthma within the last 12 months; and either on a long term controller medication for asthma, or have asthma symptoms 3 or more days per week over the past 2 weeks or nighttime asthma symptoms at least 3 times in the past month exposure to cockroach - defined as trapping at least one cockroach in a 3 day period OR visual evidence of cockroaches by field staff; and the child must sleep in the target home at least 4 nights per week on average. Caregiver ability to speak English or Spanish.
Exclusion
- Other serious medical or chronic illnesses including chronic respiratory infections that require daily medication, cardiovascular disease that requires daily medication, excluding hypertension, taking a beta-blocker, a current active smoker, currently receiving immunotherapy or plans to move within the 12 month follow-up.
Key Trial Info
Start Date :
November 15 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2028
Estimated Enrollment :
290 Patients enrolled
Trial Details
Trial ID
NCT04331353
Start Date
November 15 2020
End Date
April 30 2028
Last Update
September 9 2025
Active Locations (1)
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1
Tulane University
New Orleans, Louisiana, United States, 70112