Status:

UNKNOWN

PFS and OS of Patients With Advanced Neuroendocrine Cancer (NEN) After Systemic Treatment

Lead Sponsor:

University of Warmia and Mazury

Conditions:

Neuroendocrine Tumors

Eligibility:

All Genders

18-87 years

Brief Summary

This is a retrospective study. The analysis includes patients with advanced neuroendocrine cancer (NEN) treated with systemic therapy, because of inoperable primary tumor or/and metastasis, clinical, ...

Detailed Description

This is a retrospective study. The analysis includes patients with advanced neuroendocrine cancer (NEN) treated with systemic therapy, because of inoperable primary tumor or/and metastasis, clinical, ...

Eligibility Criteria

Inclusion

  • Adults ≥18 years old, male or female,
  • Patients with histopathological confirmation of advanced neuroendocrine cancer (NEN),
  • Patients with NETG1, NETG2 based on Ki-67,
  • Patients with diagnosed NEN, who did not receive prior treatment and were qualified to systemic treatment,
  • Patients with advanced NEN who previously received first-line systemic therapy or second-line systemic therapy,
  • Patients with advanced, inoperable NEN cancer before the treatment, during the treatment and after the treatment regardless of lines of systemic therapy,
  • Patients with diagnosed NEN and performance status (PS) ≤3 according to ECOG/WHO classification, who received systemic therapy.

Exclusion

  • Patients without histopathological confirmation of neuroendocrine carcinoma (NEN),
  • Patients with diagnosed another type of cancer or benign tumor confirmed in histopathological examination,
  • Patients treated prior with intention to treat (ITT),
  • Patients with residual disease in further clinical follow-up without active systemic treatment,
  • Patients with advanced, progressive and poor performance status, who were disqualified from further systemic treatment,
  • Patients, who finished treatment during first month or their further disease process was unknown.

Key Trial Info

Start Date :

July 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04331912

Start Date

July 1 2019

End Date

December 31 2023

Last Update

May 13 2021

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of Warmia and Mazury in Olsztyn

Olsztyn, Warmian-Masurian Voivodeship, Poland, 10-082

2

Diagnostic and Therapy Center - Gammed

Warsaw, Poland, 02-351