Status:

UNKNOWN

Analysis of Gut Microbiota in Patients With Brain Metastasis of Non-small Cell Lung Cancer Treated by Pembrolizumab Combined With Chemotherapy

Lead Sponsor:

Xiaorong Dong

Conditions:

Gut Microbiota

NSCLC

Eligibility:

All Genders

18-70 years

Phase:

PHASE1

PHASE2

Brief Summary

Analysis of Gut Microbiota in Patients With Brain Metastasis of Non-small Cell Lung Cancer Treated by Pembrolizumab Combined With Chemotherapy

Eligibility Criteria

Inclusion

  • \- non-small cell lung cancer patients with less than brain metastases Patients must have received at least the first-line anti-tumor treatment, and the front-line treatment must include chemotherapy or targeted treatment with a platinum containing combination scheme, but not anti-PD-1 / L1 treatment Patients who have not received intracranial local treatment before

Exclusion

  • \- Patients who toke major surgery within 4 weeks prior to enrollment or had ununited wounds Patients with hemorrhage in intracranial metastasis

Key Trial Info

Start Date :

April 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2022

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04333004

Start Date

April 1 2020

End Date

April 1 2022

Last Update

April 3 2020

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