Status:

COMPLETED

Anodal tDCS in Chronic Migraine With Medication Overuse

Lead Sponsor:

IRCCS National Neurological Institute "C. Mondino" Foundation

Collaborating Sponsors:

University of Pavia

Conditions:

Chronic Migraine

Medication Overuse Headache

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Non-invasive neuromodulation has been applied in several forms of primary headaches, and its usefulness has been suggested for both episodic and chronic migraine (CM). Transcranial direct current stim...

Detailed Description

The study was a randomized, double-blind, controlled trial aimed at assessing the efficacy of five daily sessions of anodal t-DCS in add-on to a standardized in-hospital detoxification protocol in pat...

Eligibility Criteria

Inclusion

  • age 18 to 65 years;
  • chronic migraine according to the criteria of the InternationaI Classification of Headache Disorders (code 1.3 ICHD-III) and Medication Overuse Headache (code 8.2 ICHD-III) present for at least 6 months at inclusion;
  • previous failure of at least three prophylactic treatments.

Exclusion

  • other neurologic or neuropsychiatric diseases;
  • other chronic painful syndromes;
  • other types of primary or secondary headaches;
  • use of a preventive medication at baseline;
  • use of central nervous system modulating drugs;
  • epilepsy;
  • metallic head implants or use of a cardiac pacemaker;
  • pregnancy or lactation.

Key Trial Info

Start Date :

January 15 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 15 2018

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04336267

Start Date

January 15 2015

End Date

January 15 2018

Last Update

April 7 2020

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