Status:

COMPLETED

The Effect of Combined Oral and Topical Analgesics to Reduce Pain Perception During Electrodiagnostic Testing

Lead Sponsor:

Aga Khan University Hospital, Pakistan

Conditions:

Pain Perception

Eligibility:

All Genders

6-18 years

Phase:

NA

Brief Summary

Electromyography (EMG) is a useful test for diagnosis and monitoring of lower motor neuron disorders. It is mostly done in conjunction with a Nerve Conduction Study (NCS). Like other invasive medical ...

Detailed Description

Objectives: To determine the effect of combined oral and topical analgesics (COTA) in reducing pain perception during NCS and EMG tests among the pediatric population. To compare the effect of COTA ...

Eligibility Criteria

Inclusion

  • \- Pediatric patients (6 months to 18 years) referred for NCS / EMG testing to the neurophysiology lab at AKUH

Exclusion

  • Patients not able to report pain scores on the scales used
  • Patients using sedatives and prior analgesics within last 24 hours of study
  • Patients with history of upper gastrointestinal tract bleed, renal disease, severe hepatic disease, glucose-6-phosphate deficiency, congenital or idiopathic methemoglobinemia
  • Patients with known sensitivity / allergy to Ibuprofen or EMLA cream or their components
  • Patients on class I antiarrhythmic drugs
  • Patients with breach of skin on topical analgesic/placebo application sites
  • Breastfeeding or sugary drink within one hour of start of study

Key Trial Info

Start Date :

December 30 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 27 2022

Estimated Enrollment :

113 Patients enrolled

Trial Details

Trial ID

NCT04337814

Start Date

December 30 2019

End Date

June 27 2022

Last Update

February 28 2023

Active Locations (1)

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Aga khan University Hospital

Karachi, Sindh, Pakistan, 7400